Article
Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk.
Arteriosclerosis, thrombosis, and vascular biology - 1 Sept 2014
Subramanian Subha, Liu Chunyu, Aviv Abraham, Ho Jennifer E, Courchesne Paul, Muntendam Pieter, Larson Martin G, Cheng Susan, Wang Thomas J, Mehta Nehal N, Levy Daniel
Abstract excerpt
OBJECTIVE: CXCL12 encodes stromal cell-derived factor 1α (SDF-1), which binds to the receptor encoded by CXCR4. Variation at the CXCL12 locus is associated with coronary artery disease and endothelial progenitor cell numbers, whereas variation at the CXCR4 locus is associated with leukocyte telomere length, which has been shown to be associated with coronary artery disease. Therefore, we examined the...
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