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Article

Steroidogenic Acute Regulatory Protein Overexpression Correlates with Protein Kinase A Activation in Adrenocortical Adenoma.

PloS one - 1 Jan 2016

Zhou Weiwei, Wu Luming, Xie Jing, Su Tingwei, Jiang Lei, Jiang Yiran, Cao Yanan, Liu Jianmin, Ning Guang, Wang Weiqing

Abstract excerpt

The association of pathological features of cortisol-producing adrenocortical adenomas (ACAs) with somatic driver mutations and their molecular classification remain unclear. In this study, we explored the association between steroidogenic acute regulatory protein (StAR) expression and the driver mutations activating cyclic adenosine monophosphate (cAMP)/protein kinase A (PKA) signaling to identify the...

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Share to Adrenal Cortex Neoplasms
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cyclic AMP-Dependent Protein Kinases

Share to GTP-Binding Protein alpha Subunits, Gs

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Source

Open in PubMed Open full text

Identifiers

PMID: 27606678
DOI: 10.1371/journal.pone.0162606
PMCID: PMC5015917

Genes

GNAS
PRKACA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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