Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

cAMP signaling in cortisol-producing adrenal adenoma.

European journal of endocrinology - 1 Oct 2015

Calebiro Davide, Di Dalmazi Guido, Bathon Kerstin, Ronchi Cristina L, Beuschlein Felix

Abstract excerpt

The cAMP signaling pathway is one of the major players in the regulation of growth and hormonal secretion in adrenocortical cells. Although its role in the pathogenesis of adrenocortical hyperplasia associated with Cushing's syndrome has been clarified, a clear involvement of the cAMP signaling pathway and of one of its major downstream effectors, the protein kinase A (PKA), in sporadic adrenocortical adenomas...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Adrenal Cortex Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Adrenocortical Adenoma

Share to Cushing Syndrome

Share to Cyclic AMP

Share to Hydrocortisone

Share to Mutation

Share to Signal Transduction

Source

Identifiers

PMID: 26139209
DOI: 10.1530/EJE-15-0353

Genes

PRKACA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

cAMP signaling in cortisol-producing adrenal adenoma.PMID 26139209Read ↗

Protein Kinase A Alterations in Adrenocortical TumorsSemantic proximity Read ↗

PRKACA: the catalytic subunit of protein kinase A and adrenocortical tumorsSemantic proximity Read ↗

Recurrent somatic mutations underlie corticotropin-independent Cushing's syndrome.Semantic proximity Read ↗

Constitutive activation of PKA catalytic subunit in adrenal Cushing's syndrome.Semantic proximity Read ↗

Novel somatic mutations in the catalytic subunit of the protein kinase A as a cause of adrenal Cushing's syndrome: a European multicentric study.Semantic proximity Read ↗

A genetic and molecular update on adrenocortical causes of Cushing syndrome.Semantic proximity Read ↗

PRKACA Mutations in Adrenal Adenomas: Genotype/Phenotype Correlations.Semantic proximity Read ↗

Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes.Semantic proximity Read ↗

Recurrent activating mutation in PRKACA in cortisol-producing adrenal tumors.Semantic proximity Read ↗

Activating PRKACB somatic mutation in cortisol-producing adenomas.Semantic proximity Read ↗

Update of Genetic and Molecular Causes of Adrenocortical Hyperplasias Causing Cushing Syndrome.Semantic proximity Read ↗

PKA catalytic subunit mutations in adrenocortical Cushing's adenoma impair association with the regulatory subunit.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.