Article
A TGF-β associated genetic score to define prognosis and platinum sensitivity in advanced epithelial ovarian cancer.
Gynecologic oncology - 1 Jan 2020
Gagno Sara, Poletto Elena, Bartoletti Michele, Quartuccio Luca, Romualdi Chiara, Garziera Marica, Scalone Simona, Sorio Roberto, Dreussi Eva, Zanusso Chiara, De Mattia Elena, Roncato Rossana, Cecchin Erika, Giorda Giorgio, De Vita Salvatore, Dal Bo Michele, Puglisi Fabio, Toffoli Giuseppe
Abstract excerpt
OBJECTIVE: Epithelial ovarian cancer (EOC) is usually diagnosed at advanced stages with highly variable clinical outcomes, even among patients with similar clinical characteristics and treatments. Host immune system plays a pivotal role in EOC pathogenesis and progression. Here, we assessed the clinical significance of 192 single nucleotide polymorphisms (SNPs) on 34 immune-system related genes in EOC patients....
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