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Article

ABCB1 G1199A polymorphism and ovarian cancer response to paclitaxel.

Journal of pharmaceutical sciences - 1 Jun 2008

Gréen Henrik, Söderkvist Peter, Rosenberg Per, Horvath György, Peterson Curt

Abstract excerpt

P-glycoprotein (P-gp), encoded by the ABCB1 gene, confers multi-drug resistance to a variety of antineoplastic agents, for example, paclitaxel. Recently, the G1199T/A polymorphism in the ABCB1 gene was shown to be important for the function of P-gp as well as for the resistance to several chemoth...

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Share to Antineoplastic Agents, Phytogenic
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Source

Identifiers

PMID: 17828752
DOI: 10.1002/jps.21169

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17828752-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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