Article
Vascular endothelial growth factor gene polymorphisms in ovarian cancer.
Gynecologic oncology - 1 May 2007
Polterauer Stephan, Grimm Christoph, Mustea Alexander, Concin Nicole, Tanner Berno, Thiel Falk, Heinze Georg, Reinthaller Alexander, Zeillinger Robert, Hefler Lukas A
Abstract excerpt
BACKGROUND: Polymorphisms within the vascular endothelial growth factor (VEGF) gene, the most important regulator of angiogenesis and vascular permeability, were shown to be independently associated with an impaired prognosis in various malignancies. No data have been reported in ovarian cancer. METHODS: In the present multi-center study, we examined three common polymorphisms within the VEGF gene (VEGF +405G/C,...
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