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Article

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

Skeletal muscle - 1 Jan 2016

Sakakibara Iori, Wurmser Maud, Dos Santos Matthieu, Santolini Marc, Ducommun Serge, Davaze Romain, Guernec Anthony, Sakamoto Kei, Maire Pascal

Abstract excerpt

BACKGROUND: Adult skeletal muscles are composed of slow and fast myofiber subtypes which each express selective genes required for their specific contractile and metabolic activity. Six homeoproteins are transcription factors regulating muscle cell fate through activation of myogenic regulatory factors and driving fast-type gene expression during embryogenesis. RESULTS: We show here that Six1 protein accumulates...

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Identifiers

PMID: 27597886
DOI: 10.1186/s13395-016-0102-x
PMCID: PMC5011358

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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