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Is hepatectomy justified for patients with RAS mutant colorectal liver metastases? An analysis of 524 patients undergoing curative liver resection.

Surgery - 1 Feb 2017

Passot Guillaume, Denbo Jason W, Yamashita Suguru, Kopetz Scott E, Chun Yun S, Maru Dipen, Overman Michael J, Brudvik Kristoffer Watten, Conrad Claudius, Aloia Thomas A, Vauthey Jean-Nicolas

Abstract excerpt

BACKGROUND: RAS mutations are associated with limited overall survival after resection of colorectal liver metastases. Our aim was to determine criteria for considering hepatectomy for patients with RAS mutant colorectal liver metastases. METHODS: Of 1,163 patients who underwent liver resection for colorectal liver metastases during 2005-2014, all patients operated on with curative intent who had known RAS...

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Identifiers

PMID: 27592215
DOI: 10.1016/j.surg.2016.07.032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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