Article
Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations.
European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology - 1 Sept 2016
Passot G, Chun Y S, Kopetz S E, Overman M J, Conrad C, Aloia T A, Vauthey J-N
Abstract excerpt
BACKGROUND: After resection of colorectal liver metastases (CLM), RAS mutations are associated with modest survival benefit and second-line chemotherapy confers limited hope for cure. OBJECTIVE: To evaluate the impact of RAS mutation after second-line chemotherapy for patients undergoing potentially curative liver resection for CLM. METHODS: Among 1357 patients operated for CLM between January 2005 and November...
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