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Article

Reevaluating the prognostic value of RAS mutation status in patients with resected liver metastases from colorectal cancer: A systematic review and meta-analysis.

Journal of hepato-biliary-pancreatic sciences - 1 Aug 2021

Pikoulis Emmanouil, Papaconstantinou Dimitrios, Pikouli Anastasia, Wang Jane, Theodoridis Charalampos, Margonis Georgios Antonios

Abstract excerpt

BACKGROUND: Although the value of Rat Sarcoma Oncogene (RAS) mutation status in predicting long-term outcomes in patients with colorectal liver metastases (CRLM) is widely accepted, the magnitude of its impact has recently been challenged by three large cohort studies. The aim of this meta-analysis is to reevaluate the impact of RAS mutations on overall survival (OS) and disease-free survival (DFS) in patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34115442
DOI: 10.1002/jhbp.1007

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