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Article

Epistatic SNP interaction of ERCC6 with ERCC8 and their joint protein expression contribute to gastric cancer/atrophic gastritis risk.

Oncotarget - 27 Jun 2017

Jing Jing-Jing, Lu You-Zhu, Sun Li-Ping, Liu Jing-Wei, Gong Yue-Hua, Xu Qian, Dong Nan-Nan, Yuan Yuan

Abstract excerpt

Excision repair cross-complementing group 6 and 8 (ERCC6 and ERCC8) are two indispensable genes for the initiation of transcription-coupled nucleotide excision repair pathway. This study aimed to evaluate the interactions between single nucleotide polymorphisms of ERCC6 (rs1917799) and ERCC8 (rs158572 and rs158916) in gastric cancer and its precancerous diseases. Besides, protein level analysis were performed to...

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Source

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Identifiers

PMID: 28562347
DOI: 10.18632/oncotarget.17814
PMCID: PMC5522134

Genes

ERCC6
ERCC8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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