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Article

TGFΒ-induced transcription in cancer

9 Sept 2016

Abstract excerpt

The Transforming Growth Factor-beta (TGFβ) pathway mediates a broad spectrum of cellular processes and is involved in several diseases, including cancer. TGFβ has a dual role in tumours, acting as a tumour suppressor in the early phase of tumorigenesis and as a tumour promoter in more advanced stages. In this review, we discuss the effects of TGFβ-driven transcription on all stages of tumour progression, with...

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PMID: 27586372
DOI: 10.1016/j.semcancer.2016.08.009

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