Distinct metabolic network states manifest in the gene expression profiles of pediatric inflammatory bowel disease patients and controls.

Abstract excerpt

Information on biological networks can greatly facilitate the function-orientated interpretation of high-throughput molecular data. Genome-wide metabolic network models of human cells, in particular, can be employed to contextualize gene expression profiles of patients with the goal of both, a better understanding of individual etiologies and an educated reclassification of (clinically defined) phenotypes. We...

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