Article
A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
2 Sept 2016
Abstract excerpt
CRISPR/Cas systems are widespread RNA-mediated prokaryotic adaptive immune systems providing protection against invading nucleic acids 1 . However, throughout evolution, this host defense system has not resulted in the eradication of phages, suggesting that phages have evolved counter strategies to thrive within bacteria despite these mechanisms 2 . Thus, both bacterial CRISPR system and phage anti-CRISPR system...
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