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Article

Diversity, classification and evolution of CRISPR-Cas systems.

Current opinion in microbiology - 1 Jun 2017

Koonin Eugene V, Makarova Kira S, Zhang Feng

Abstract excerpt

The bacterial and archaeal CRISPR-Cas systems of adaptive immunity show remarkable diversity of protein composition, effector complex structure, genome locus architecture and mechanisms of adaptation, pre-CRISPR (cr)RNA processing and interference. The CRISPR-Cas systems belong to two classes, with multi-subunit effector complexes in Class 1 and single-protein effector modules in Class 2. Concerted genomic and...

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Identifiers

PMID: 28605718
DOI: 10.1016/j.mib.2017.05.008
PMCID: PMC5776717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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