Article
DNA and RNA interference mechanisms by CRISPR-Cas surveillance complexes.
FEMS microbiology reviews - 1 May 2015
Plagens André, Richter Hagen, Charpentier Emmanuelle, Randau Lennart
Abstract excerpt
The CRISPR (clustered regularly interspaced short palindromic repeats)-Cas (CRISPR-associated) adaptive immune systems use small guide RNAs, the CRISPR RNAs (crRNAs), to mark foreign genetic material, e.g. viral nucleic acids, for degradation. Archaea and bacteria encode a large variety of Cas pr...
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