Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Centrality of Mitochondria in the Pathogenesis and Treatment of Parkinson's Disease

7 Apr 2014

Abstract excerpt

Parkinson's disease (PD) is an incurable neurodegenerative disorder leading to progressive motor impairment and for which there is no cure. From the first postmortem account describing a lack of mitochondrial complex I in the substantia nigra of PD sufferers, the direct association between mitochondrial dysfunction and death of dopaminergic neurons has ever since been consistently corroborated. In this review, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mitochondrial Function and Pathology
Share to Neurological diseases and metabolism
Share to Parkinson's Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24703487
DOI: 10.1111/cns.12264

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Centrality of Mitochondria in the Pathogenesis and Treatment of Parkinson's DiseasePMID 24703487Read ↗

Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potentialSemantic proximity Read ↗

Targeting Mitochondria for Neuroprotection in Parkinson's DiseaseSemantic proximity Read ↗

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic PerspectivesSemantic proximity Read ↗

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis.Semantic proximity Read ↗

The Parkinson Disease Mitochondrial HypothesisSemantic proximity Read ↗

Mitochondrial Dysfunction and Parkinson’s Disease: Pathogenesis and Therapeutic StrategiesSemantic proximity Read ↗

Pathological and Therapeutic Advances in Parkinson’s Disease: Mitochondria in the InterplaySemantic proximity Read ↗

Targeting Mitochondrial Impairment in Parkinson's Disease: Challenges and OpportunitiesSemantic proximity Read ↗

Mitochondrial therapies for Parkinson's diseaseSemantic proximity Read ↗

Mitochondrial Dysfunction in Parkinson's Disease: Pathogenesis and NeuroprotectionSemantic proximity Read ↗

Significance of Mitochondrial Dysfunction in the Pathogenesis of Parkinson's DiseaseSemantic proximity Read ↗

Mitochondrial dysfunction and possible treatments in Parkinson's disease—a reviewSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.