Article
DNA methylation array analyses identified breast cancer-associated HYAL2 methylation in peripheral blood.
International journal of cancer - 15 Apr 2015
Yang Rongxi, Pfütze Katrin, Zucknick Manuela, Sutter Christian, Wappenschmidt Barbara, Marme Frederik, Qu Bin, Cuk Katarina, Engel Christoph, Schott Sarah, Schneeweiss Andreas, Brenner Hermann, Claus Rainer, Plass Christoph, Bugert Peter, Hoth Markus, Sohn Christof, Schmutzler Rita, Bartram Claus R, Burwinkel Barbara
Abstract excerpt
Breast cancer (BC) is the leading cause of cancer-related mortality in women worldwide. Changes in DNA methylation in peripheral blood could be associated with malignancy at early stage. However, the BC-associated DNA methylation signatures in peripheral blood were largely unknown. Here, we performed a genome-wide methylation screening and identified a BC-associated differentially methylated CpG site cg27091787...
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