Article
Phenotypically Enriched Genotypic Imputation in Genetic Association Tests.
Human heredity - 1 Jan 2016
Zhuang Wei Vivian, Murabito Joanne M, Lunetta Kathryn L
Abstract excerpt
BACKGROUND: In longitudinal epidemiological studies there may be individuals with rich phenotype data who die or are lost to follow-up before providing DNA for genetic studies. Often, the genotypic and phenotypic data of the relatives are available. Two strategies for analyzing the incomplete data are to exclude ungenotyped subjects from analysis (the complete-case method, CC) and to include phenotyped but...
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