Article
Evaluation of potential power gain with imputed genotypes in genome-wide association studies.
Human heredity - 1 Jan 2009
Becker Tim, Flaquer Antonia, Brockschmidt Felix F, Herold Christine, Steffens Michael
Abstract excerpt
BACKGROUND: With the beginning of the era of genome-wide association studies methods to obtain 'in silico' genotypes have gained importance. In this context, an evaluation of genome-wide power levels of current marker panels and the power gain achievable with imputed genotypes are of high interes...
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