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Article

Evaluation of potential power gain with imputed genotypes in genome-wide association studies.

Human heredity - 1 Jan 2009

Becker Tim, Flaquer Antonia, Brockschmidt Felix F, Herold Christine, Steffens Michael

Abstract excerpt

BACKGROUND: With the beginning of the era of genome-wide association studies methods to obtain 'in silico' genotypes have gained importance. In this context, an evaluation of genome-wide power levels of current marker panels and the power gain achievable with imputed genotypes are of high interest. METHODS: Power for single-marker analysis of imputed genotypes is evaluated via a simulation study based on HapMap...

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PMID: 19339783
DOI: 10.1159/000210446

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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