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Article

Coronary arterial BK channel dysfunction exacerbates ischemia/reperfusion-induced myocardial injury in diabetic mice.

Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme - 1 Sept 2016

Lu Tong, Jiang Bin, Wang Xiao-Li, Lee Hon-Chi

Abstract excerpt

The large conductance Ca(2+)-activated K(+) (BK) channels, abundantly expressed in coronary artery smooth muscle cells (SMCs), play a pivotal role in regulating coronary circulation. A large body of evidence indicates that coronary arterial BK channel function is diminished in both type 1 and type 2 diabetes. However, the consequence of coronary BK channel dysfunction in diabetes is not clear. We hypothesized...

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Identifiers

PMID: 27574914
DOI: 10.1139/apnm-2016-0048

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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