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Article

High-resolution mutational profiling suggests the genetic validity of glioblastoma patient-derived pre-clinical models.

PloS one - 1 Jan 2013

Yost Shawn E, Pastorino Sandra, Rozenzhak Sophie, Smith Erin N, Chao Ying S, Jiang Pengfei, Kesari Santosh, Frazer Kelly A, Harismendy Olivier

Abstract excerpt

Recent advances in the ability to efficiently characterize tumor genomes is enabling targeted drug development, which requires rigorous biomarker-based patient selection to increase effectiveness. Consequently, representative DNA biomarkers become equally important in pre-clinical studies. Howeve...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23441165
DOI: 10.1371/journal.pone.0056185
PMCID: PMC3575368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23441165-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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