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Article

Influenza B virus M2 protein can functionally replace its influenza A virus counterpart in promoting virus replication.

Virology - 1 Nov 2016

Wanitchang Asawin, Wongthida Phonphimon, Jongkaewwattana Anan

Abstract excerpt

The M2 protein (AM2 and BM2) of influenza A and B viruses function as a proton channel essential for viral replication. They also carry a cytoplasmic tail whose functions are not fully delineated. It is currently unknown whether these proteins could be replaced functionally in a viral context. Here, we generated single-cycle influenza A viruses (scIAV-ΔHA) carrying various M2-2A-mCherry constructs in the segment...

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Source

Identifiers

PMID: 27567258
DOI: 10.1016/j.virol.2016.08.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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