Article
Human Annexin A6 Interacts with Influenza A Virus Protein M2 and Negatively Modulates Infection
24 Nov 2011
Abstract excerpt
The influenza A virus M2 ion channel protein has the longest cytoplasmic tail (CT) among the three viral envelope proteins and is well conserved between different viral strains. It is accessible to the host cellular machinery after fusion with the endosomal membrane and during the trafficking, assembly, and budding processes. We hypothesized that identification of host cellular interactants of M2 CT could help us...
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