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Article

Proton and cation transport activity of the M2 proton channel from influenza A virus.

Proceedings of the National Academy of Sciences of the United States of America - 31 Aug 2010

Leiding Thom, Wang Jun, Martinsson Jonas, DeGrado William F, Arsköld Sindra Peterson

Abstract excerpt

The M2 protein is a small, single-span transmembrane (TM) protein from the influenza A virus. This virus enters cells via endosomes; as the endosomes mature and become more acidic M2 facilitates proton transport into the viral interior, thereby disrupting matrix protein/RNA interactions required...

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Identifiers

PMID: 20713739
DOI: 10.1073/pnas.1009997107
PMCID: PMC2932607

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20713739-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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