Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability.

Cell host & microbe - 12 Feb 2014

Beale Rupert, Wise Helen, Stuart Amanda, Ravenhill Benjamin J, Digard Paul, Randow Felix

Abstract excerpt

Autophagy recycles cellular components and defends cells against intracellular pathogens. While viruses must evade autophagocytic destruction, some viruses can also subvert autophagy for their own benefit. The ability of influenza A virus (IAV) to evade autophagy depends on the Matrix 2 (M2) ion-...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Host-Pathogen Interactions
Share to Influenza A virus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microtubule-Associated Proteins

Share to Mutant Proteins

Share to Protein Interaction Domains and Motifs

Share to Viral Matrix Proteins

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 24528869
DOI: 10.1016/j.chom.2014.01.006
PMCID: PMC3991421

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24528869-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A LC3-interacting motif in the influenza A virus M2 protein is required to subvert autophagy and maintain virion stability.PMID 24528869Read ↗

Mammalian cells use the autophagy process to restrict avian influenza virus replicationSemantic proximity Read ↗

Autophagy Promotes Replication of Influenza A Virus In VitroSemantic proximity Read ↗

TNK2/ACK1 Strengthen Influenza A Virus Infection by Blocking Viral Matrix 2 Protein(M2) into Lysosome to DegradationSemantic proximity Read ↗

The battle for autophagy between host and influenza A virusSemantic proximity Read ↗

Contribution of autophagy machinery factors to HCV and SARS-CoV-2 replication organelle formationSemantic proximity Read ↗

Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagySemantic proximity Read ↗

Coxsackievirus infection induces a non-canonical autophagy independent of the ULK and PI3K complexesSemantic proximity Read ↗

The matrix protein of lyssavirus hijacks autophagosome for efficient egress by recruiting NEDD4 through its PPxY motifSemantic proximity Read ↗

The nucleoprotein of influenza A virus inhibits the innate immune response by inducing mitophagySemantic proximity Read ↗

Identification of a Novel Splice Variant Form of the Influenza A Virus M2 Ion Channel with an Antigenically Distinct EctodomainSemantic proximity Read ↗

Fish herpesvirus KLP manipulates Beclin1 to selectively degrade MITA through a precise autophagic manner for immune evasionSemantic proximity Read ↗

A Glu-Glu-Tyr sequence in the cytoplasmic tail of the M2 protein renders IAV susceptible to restriction of HA-M2 association in primary human macrophagesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.