Article
Two forms of death in ageing Caenorhabditis elegans.
Nature communications - 23 May 2017
Zhao Yuan, Gilliat Ann F, Ziehm Matthias, Turmaine Mark, Wang Hongyuan, Ezcurra Marina, Yang Chenhao, Phillips George, McBay David, Zhang William B, Partridge Linda, Pincus Zachary, Gems David
Abstract excerpt
Ageing generates senescent pathologies, some of which cause death. Interventions that delay or prevent lethal pathologies will extend lifespan. Here we identify life-limiting pathologies in Caenorhabditis elegans with a necropsy analysis of worms that have died of old age. Our results imply the presence of multiple causes of death. Specifically, we identify two classes of corpse: early deaths with a swollen...
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