Article
Comparison of Ramosetron and Palonosetron for Preventing Nausea and Vomiting after Spinal Surgery: Association With ABCB1 Polymorphisms.
Journal of neurosurgical anesthesiology - 1 Oct 2017
Song Jong Wook, Shim Jae-Kwang, Choi Seung Ho, Soh Sarah, Jang Jaewon, Kwak Young Lan
Abstract excerpt
BACKGROUND: Adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) polymorphisms may influence 5-hydroxytryptamine receptor antagonist efficacy by altering their efflux transportation. We evaluated the influence of ABCB1 polymorphisms on the efficacy of ramosetron compared with palonosetron in managing postoperative nausea and vomiting (PONV) in patients who received intravenous patient-controlled...
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