Article
Association of ABCB1 polymorphisms with the efficacy of ondansetron for postoperative nausea and vomiting.
Anaesthesia - 1 Oct 2010
Choi E M, Lee M G, Lee S H, Choi K W, Choi S H
Abstract excerpt
We investigated whether the 2677G>T/A and 3435C>T polymorphisms of adenosine triphosphate-binding cassette subfamily B member 1 (ABCB1) affect the efficacy of ondansetron to prevent postoperative nausea and vomiting. One hundred and ninety-eight patients undergoing general anaesthesia were enrolled. Thirty minutes before the end of surgery, 0.1 mg.kg⁻¹ ondansetron was administered intravenously. The incidence of...
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