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Article

Genetic polymorphisms in the ABCB1 gene and the effects of fentanyl in Koreans.

Clinical pharmacology and therapeutics - 1 Apr 2007

Park H-J, Shinn H K, Ryu S H, Lee H-S, Park C-S, Kang J-H

Abstract excerpt

P-glycoprotein (PGP) is a polymorphic transporter encoded by the ABCB1 gene that contributes to the access of xenobiotics into the brain. There is no report on associations between genetic polymorphisms in ABCB1 and the clinical effects of fentanyl, although fentanyl may be a substrate of PGP. One hundred and twenty-six (126) unrelated Korean patients under spinal anesthesia with intravenous fentanyl (2.5...

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Source

Identifiers

PMID: 17192767
DOI: 10.1038/sj.clpt.6100046

Genes

ABCB1
PGP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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