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DNA methylation profiling in human lung tissue identifies genes associated with COPD

26 Aug 2016

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a smoking-related disease characterized by genetic and phenotypic heterogeneity. Although association studies have identified multiple genomic regions with replicated associations to COPD, genetic variation only partially explains the susceptibility to lung disease, and suggests the relevance of epigenetic investigations. We performed genome-wide DNA methylation...

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PMID: 27564456
DOI: 10.1080/15592294.2016.1226451

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