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Article

Application of the FISH method and high-density SNP arrays to assess genetic changes in neuroblastoma-research by one institute.

Acta biochimica Polonica - 1 Jan 2024

Winnicka Dorota, Skowera Paulina, Stelmach Magdalena, Styka Borys, Lejman Monika

Abstract excerpt

Neuroblastoma is the most common extracranial solid tumor in children. Amplification of the MYCN gene has been observed in approximately 20%-30% of tumors. It is strongly correlated with advanced-stage disease, rapid tumor progression, resistance to chemotherapy and poor outcomes independent of patient age and stage of advanced disease. MYCN amplification identifies high-risk patients. To assess neuroblastoma...

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Identifiers

PMID: 39049899
DOI: 10.3389/abp.2024.12821
PMCID: PMC11267511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Application of the FISH method and high-density SNP arrays to assess genetic changes in neuroblastoma-research by one institute.PMID 39049899Read ↗

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