Article
Whole-genome characterization in pedigreed non-human primates using genotyping-by-sequencing (GBS) and imputation.
BMC genomics - 24 Aug 2016
Bimber Benjamin N, Raboin Michael J, Letaw John, Nevonen Kimberly A, Spindel Jennifer E, McCouch Susan R, Cervera-Juanes Rita, Spindel Eliot, Carbone Lucia, Ferguson Betsy, Vinson Amanda
Abstract excerpt
BACKGROUND: Rhesus macaques are widely used in biomedical research, but the application of genomic information in this species to better understand human disease is still in its infancy. Whole-genome sequence (WGS) data in large pedigreed macaque colonies could provide substantial experimental power for genetic discovery, but the collection of WGS data in large cohorts remains a formidable expense. Here, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
