Article
The value of extended pedigrees for next-generation analysis of complex disease in the rhesus macaque.
ILAR journal - 1 Jan 2013
Vinson Amanda, Prongay Kamm, Ferguson Betsy
Abstract excerpt
Complex diseases (e.g., cardiovascular disease and type 2 diabetes, among many others) pose the biggest threat to human health worldwide and are among the most challenging to investigate. Susceptibility to complex disease may be caused by multiple genetic variants (GVs) and their interaction, by environmental factors, and by interaction between GVs and environment, and large study cohorts with substantial...
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