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Article

Antineutrophil antibodies define clinical and genetic subgroups in primary sclerosing cholangitis.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2017

Hov Johannes R, Boberg Kirsten M, Taraldsrud Eli, Vesterhus Mette, Boyadzhieva Maria, Solberg Inger Camilla, Schrumpf Erik, Vatn Morten H, Lie Benedicte A, Molberg Øyvind, Karlsen Tom H

Abstract excerpt

BACKGROUND & AIMS: The strongest genetic risk factors in primary sclerosing cholangitis (PSC) are encoded in the HLA complex. Antineutrophil cytoplasmic antibodies (ANCA) have been reported in up to 94% of PSC patients, but their clinical significance and immunogenetic basis are ill defined. We aimed to characterize clinical and genetic associations of ANCA in PSC. METHODS: Antineutrophil cytoplasmic antibodies...

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Share to Antibodies, Antineutrophil Cytoplasmic
Share to Cholangitis, Sclerosing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Fluorescent Antibody Technique, Indirect

Share to HLA-B27 Antigen

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Identifiers

PMID: 27558072
DOI: 10.1111/liv.13238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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