Article
Somatic mutations in plasma cell-free DNA are diagnostic markers for esophageal squamous cell carcinoma recurrence.
Oncotarget - 20 Sept 2016
Ueda Masami, Iguchi Tomohiro, Masuda Takaaki, Nakahara Yujiro, Hirata Hidenari, Uchi Ryutaro, Niida Atsushi, Momose Kota, Sakimura Shotaro, Chiba Kenichi, Eguchi Hidetoshi, Ito Shuhei, Sugimachi Keishi, Yamasaki Makoto, Suzuki Yutaka, Miyano Satoru, Doki Yuichiro, Mori Masaki, Mimori Koshi
Abstract excerpt
OBJECTIVES: Esophageal squamous cell carcinoma (ESCC) is one of the most aggressive malignancies owing to the high frequency of tumor recurrence. The identification of markers for early ESCC diagnosis and prediction of recurrence is expected to improve the long-term prognosis. Therefore, we searched for associations between tumor recurrence and cell-free DNA (cfDNA) mutations in blood plasma, which contains...
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