Article
Genomic characterization reveals potential biomarkers in nasopharyngeal carcinoma patients with relapse.
Expert review of molecular diagnostics - 1 Nov 2020
Cho William C S, Tse Ka-Po, Ngan Roger K C, Cheuk Wah, Ma Victor W S, Yang Yi-Ting, Yip Timothy T C, Tan Kien Thiam, Chen Shu-Jen
Abstract excerpt
BACKGROUND: Although the majority of nasopharyngeal carcinoma (NPC) patients demonstrate favorable outcomes after radiotherapy and/or chemotherapy, about 8-10% of patients will develop recurrent disease, and genomic alterations (GAs) associated with the recurrence are unclear. METHODS: This study investigated the GAs in the paired primary tumors and recurrent tumors of 7 NPC patients with relapse, as well as the...
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