Article
Molecular background of oligodendroglioma: 1p/19q, IDH, TERT, CIC and FUBP1.
CNS oncology - 1 Jan 2015
Cahill Daniel P, Louis David N, Cairncross John Gregory
Abstract excerpt
Oligodendroglioma is the quintessential molecularly-defined brain tumor. The characteristic whole-arm loss of the long arm of chromosome 1 and the short arm of chromosome 19 (1p/19q-codeletion) within the genome of these tumors facilitated the reproducible molecular identification of this subcategory of gliomas. More recently, recurrent molecular genetic alterations have been identified to occur concurrently with...
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