Article
Expanding the knowledge of the chemical structure of glycoconjugates from Trypanosoma cruzi TcI genotype. Contribution to taxonomic studies.
Anais da Academia Brasileira de Ciencias - 1 Sept 2016
Fonseca Leonardo M, Garcez Tatiana C, Penha Luciana, Freire-DE-Lima Leonardo, Maes Emmanuel, Costa Kelli M, Mendonça-Previato Lucia, Previato Jose O
Abstract excerpt
One of the main obstacles to the treatment of Chagas disease is the genetic and phenotypical variance displayed by T. cruzi strains, resulting in differences in morphology, virulence, pathogenicity and drug susceptibility. To better understand the role of glycoconjungates in Chagas disease, we performed the molecular characterization of the O-linked chains from mucins and glycoinositolphospholipids (GIPLs) of the...
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