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Article

The surface coat of the mammal-dwelling infective trypomastigote stage of Trypanosoma cruzi is formed by highly diverse immunogenic mucins.

The Journal of biological chemistry - 16 Apr 2004

Buscaglia Carlos A, Campo Vanina A, Di Noia Javier M, Torrecilhas Ana C T, De Marchi Cláudia R, Ferguson Michael A J, Frasch Alberto C C, Almeida Igor C

Abstract excerpt

A thick coat of mucin-like glycoproteins covers the surface of Trypanosoma cruzi and plays a crucial role in parasite protection and infectivity and host immunomodulation. The appealing candidate genes coding for the mucins of the mammal-dwelling stages define a heterogeneous family termed TcMUC, which comprises up to 700 members, thus precluding a genetic approach to address the protein core identity. Here, we...

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Identifiers

PMID: 14749325
DOI: 10.1074/jbc.M314051200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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