Article
Trypanosoma cruzi surface mucins with exposed variant epitopes.
The Journal of biological chemistry - 8 Sept 2000
Pollevick G D, Di Noia J M, Salto M L, Lima C, Leguizamón M S, de Lederkremer R M, Frasch A C
Abstract excerpt
The protozoan parasite Trypanosoma cruzi, the agent of Chagas disease, has a large number of mucin molecules on its surface, whose expression is regulated during the life cycle. These mucins are the main acceptors of sialic acid, a monosaccharide that is required by the parasite to infect and survive in the mammalian host. A large mucin-like gene family named TcMUC containing about 500 members has been identified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.