Article
Impact of ATM rs1801516 on late skin reactions of radiotherapy for breast cancer: Evidences from a cohort study and a trial sequential meta-analysis.
PloS one - 1 Jan 2019
Terrazzino Salvatore, Cargnin Sarah, Deantonio Letizia, Pisani Carla, Masini Laura, Canonico Pier Luigi, Genazzani Armando A, Krengli Marco
Abstract excerpt
The relationship between the ataxia-telangiectasia mutated (ATM) rs1801516 gene polymorphism and risk of radiation-induced late skin side effects remains a highly debated issue. In the present study, we assessed the role of ATM rs1801516 as risk factor for radiation-induced fibrosis and telangiectasia, using the LENT-SOMA scoring scale in 285 breast cancer patients who received radiotherapy after breast...
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