Article
Dysregulated myogenesis and autophagy in genetically induced pulmonary emphysema
2021-07-09
Abstract excerpt
Patients with chronic obstructive pulmonary disease (COPD)-pulmonary emphysema often develop locomotor muscle dysfunction, which is independently associated with disability and higher mortality in that population. Muscle dysfunction entails reduced muscle mass and force-generation capacity, which are influenced by fibers integrity. Myogenesis, which is muscle turnover driven by progenitor cells such as satellite c...
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Identifiers and source
- Literature Corpus work
- f9f30d04-fd3b-5396-adca-ef127a18e8fb
- DOI
- 10.1101/2021.07.08.450201