Article
Balancing selection and genetic drift create unusual patterns of MHCIIβ variation in Galápagos mockingbirds.
Molecular ecology - 1 Oct 2016
Vlček Jakub, Hoeck Paquita E A, Keller Lukas F, Wayhart Jessica P, Dolinová Iva, Štefka Jan
Abstract excerpt
The extracellular subunit of the major histocompatibility complex MHCIIβ plays an important role in the recognition of pathogens and the initiation of the adaptive immune response of vertebrates. It is widely accepted that pathogen-mediated selection in combination with neutral micro-evolutionary forces (e.g. genetic drift) shape the diversity of MHCIIβ, but it has proved difficult to determine the relative...
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