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Article

Evidence for selection maintaining MHC diversity in a rodent species despite strong density fluctuations.

Immunogenetics - 1 Jul 2016

Schuster Andrea C, Herde Antje, Mazzoni Camila J, Eccard Jana A, Sommer Simone

Abstract excerpt

Strong spatiotemporal variation in population size often leads to reduced genetic diversity limiting the adaptive potential of individual populations. Key genes of adaptive variation are encoded by the immune genes of the major histocompatibility complex (MHC) playing an essential role in parasite resistance. How MHC variation persists in rodent populations that regularly experience population bottlenecks remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27225422
DOI: 10.1007/s00251-016-0916-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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