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Recent selection created distinctive variability patterns on MHC class II loci in three dolphin species from the Mediterranean Sea.

Developmental and comparative immunology - 1 Jan 2024

Arbanasić Haidi, Medrano-González Luis, Hrenar Tomica, Mikelić Ana, Gomerčić Tomislav, Svetličić Ida, Pavlinec Željko, Đuras Martina, Galov Ana

Abstract excerpt

The major histocompatibility complex (MHC) includes highly polymorphic genes involved in antigen presentation, which is crucial for adaptive immune response. They represent fitness related genetic markers particularly informative for populations exposed to environmental challenges. Here we analyse the diversity and evolutionary traits of MHC class II DQA and DQB genes in the dolphins Stenella coeruleoalba and...

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PMID: 37832898
DOI: 10.1016/j.dci.2023.105079

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