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Article

Possible relationship between IL28B rs12979860 and TLR2 -196 to -174 del/ins polymorphisms and the liver fibrosis stage in hepatitis C patients.

Archives of virology - 1 Jan 2022

Öksüz Zehra, Üçbilek Enver, Serin Mehmet Sami, Yaraş Serkan, Temel Gülhan Örekici, Sezgin Orhan

Abstract excerpt

It has been shown that host factors play an important role in the progression of hepatitis C virus (HCV) infection. Toll-like receptor 2 (TLR2) del and interleukin 28B (IL28B) T alleles can mediate liver inflammation and pathogenesis of hepatocellular carcinoma. In the present study, the possible relationship between the IL28B rs12979860 C/T and TLR2 -196 to -174 del/ins gene variants and different fibrosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34817649
DOI: 10.1007/s00705-021-05302-9

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