Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction.

The Journal of experimental medicine - 3 Jun 2013

Bibert Stéphanie, Roger Thierry, Calandra Thierry, Bochud Murielle, Cerny Andreas, Semmo Nasser, Duong François H T, Gerlach Tilman, Malinverni Raffaele, Moradpour Darius, Negro Francesco, Müllhaupt Beat, Bochud Pierre-Yves

Abstract excerpt

Approximately 3% of the world population is chronically infected with the hepatitis C virus (HCV), with potential development of cirrhosis and hepatocellular carcinoma. Despite the availability of new antiviral agents, treatment remains suboptimal. Genome-wide association studies (GWAS) identifie...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemokine CXCL10
Share to Hepacivirus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C, Chronic

Share to Interferon-gamma

Share to Interferons

Share to Interleukins

Share to Leukocytes, Mononuclear

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 23712427
DOI: 10.1084/jem.20130012
PMCID: PMC3674704

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23712427-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IL28B expression depends on a novel TT/-G polymorphism which improves HCV clearance prediction.PMID 23712427Read ↗

Genetics of IL28B and HCV--response to infection and treatment.Semantic proximity Read ↗

IL28B polymorphism and genetic biomarkers of viral clearance in hepatitis C virus infection.Semantic proximity Read ↗

Association of rs12979860 and rs8099917 polymorphisms at IL28B gene with chronic hepatitis B and C, and non-viral liver disease patients IL28B rs8099917 G risk factor for hepatitis B patientsSemantic proximity Read ↗

Association of Interleukin 28B Polymorphism with Clearance of Hepatitis C Virus: A Mini Review.Semantic proximity Read ↗

A single nucleotide polymorphism associated with hepatitis C virus infections located in the distal region of the IL28B promoter influences NF-κB-mediated gene transcription.Semantic proximity Read ↗

IL28B in hepatitis C virus infection: translating pharmacogenomics into clinical practice.Semantic proximity Read ↗

Association of genetic variation in IL28B with hepatitis C treatment-induced viral clearance in the Chinese Han population.Semantic proximity Read ↗

The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients.Semantic proximity Read ↗

Role of IL28B for chronic hepatitis C treatment toward personalized medicine.Semantic proximity Read ↗

IL28B single nucleotide polymorphisms in the treatment of hepatitis C.Semantic proximity Read ↗

Interleukin 28B.rs12979860 genotype does not affect hepatitis C viral load in Egyptians with genotype 4 chronic infection.Semantic proximity Read ↗

Deciphering the interleukin 28B variants that better predict response to pegylated interferon-α and ribavirin therapy in HCV/HIV-1 coinfected patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.