Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse.

The Journal of pathology - 1 Nov 2016

Wu Rong, Zhai Yali, Kuick Rork, Karnezis Anthony N, Garcia Paloma, Naseem Anum, Hu Tom C, Fearon Eric R, Cho Kathleen R

Abstract excerpt

Endometrioid carcinoma (EC) is a relatively indolent ovarian carcinoma subtype that is nonetheless deadly if detected late. Existing genetically engineered mouse models (GEMMs) of the disease, based on transformation of the ovarian surface epithelium (OSE), take advantage of known ovarian EC driver gene lesions, but do not fully recapitulate the disease features seen in patients. An EC model in which the Apc and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenomatous Polyposis Coli Protein
Share to Carcinoma, Endometrioid

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Ovarian Epithelial

Share to Fallopian Tubes

Share to Integrases

Share to Neoplasms, Glandular and Epithelial

Share to Tamoxifen

Source

Open in PubMed Open full text

Identifiers

PMID: 27538791
DOI: 10.1002/path.4783
PMCID: PMC5071155

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of oviductal versus ovarian epithelial cell of origin on ovarian endometrioid carcinoma phenotype in the mouse.PMID 27538791Read ↗

High-grade serous carcinomas arise in the mouse oviduct via defects linked to the human disease.Semantic proximity Read ↗

Precious GEMMs: emergence of faithful models for ovarian cancer researchSemantic proximity Read ↗

IS "OVARIAN" CANCER A MISNOMER? EXPLORING OVARIAN CANCER ORIGINS IN THE MOUSE.Semantic proximity Read ↗

Genetically-defined ovarian cancer mouse models.Semantic proximity Read ↗

Both Fallopian Tube and Ovarian Surface Epithelium Can Act as Cell-of-Origin for High Grade Serous Ovarian CarcinomaSemantic proximity Read ↗

MYC is sufficient to generate mid-life high-grade serous ovarian and uterine serous carcinomas in a p53-R270H mouse modelSemantic proximity Read ↗

Genetically engineered mouse models for epithelial ovarian cancer: are we there yet?Semantic proximity Read ↗

Assessing the origin of high-grade serous ovarian cancer using CRISPR-modification of mouse organoids.Semantic proximity Read ↗

Epithelial ovarian cancer: Focus on genetics and animal modelsSemantic proximity Read ↗

Both fallopian tube and ovarian surface epithelium are cells-of-origin for high-grade serous ovarian carcinoma.Semantic proximity Read ↗

Tumorigenesis and peritoneal colonization from fallopian tube epitheliumSemantic proximity Read ↗

Oviduct-specific glycoprotein is a molecular marker for invasion in endometrial tumorigenesis identified using a relevant mouse model.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.