Article
Changes in Bacillus anthracis CodY regulation under host-specific environmental factor deprived conditions.
BMC genomics - 17 Aug 2016
Kim Se Kye, Jung Kyoung Hwa, Chai Young Gyu
Abstract excerpt
BACKGROUND: Host-specific environmental factors induce changes in Bacillus anthracis gene transcription during infection. A global transcription regulator, CodY, plays a pivotal role in regulating central metabolism, biosynthesis, and virulence in B. anthracis. In this study, we utilized RNA-sequencing to assess changes in the transcriptional patterns of CodY-regulated B. anthracis genes in response to three...
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